| Swine | Laying hen | Ruminant | Aquaculture | Broiler | ||
What is Tipek (Laying Hens)? |
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Tipek (Laying Hens) is a functional bioactive peptide product used as a laying hen and breeder feed additive. Its core active ingredient is recombinant Gallus Epidermal Growth Factor (gEGF) — gene-engineered and produced via precision yeast fermentation, with a sequence identical to the bird's own endogenous EGF for maximum EGFR binding affinity and biological activity.
In intensive laying hen production, hens face continuous stress from high-density housing, long laying cycles, feed transitions, and environmental challenges. Each episode of intestinal damage — whether from pathogens, mycotoxins, or production stress — reduces the absorptive efficiency for calcium, phosphorus, and protein: the direct nutritional inputs for eggshell formation, egg weight, and laying rate. Tipek provides continuous intestinal support to maintain peak performance longer and slow the age-related decline in egg quality. |
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How Does Tipek (Laying Hens) Work?
gEGF binds to EGF receptors expressed throughout the intestinal epithelium, triggering autophosphorylation and activation of downstream signaling pathways that drive four measurable outcomes:
Promote and Maintain Intestinal Development Maintains enterocyte metabolism and absorptive function throughout the laying cycle. Supports villus height and intestinal length to maximize the surface available for nutrient absorption — particularly calcium and phosphorus critical for eggshell formation. Repair Epithelial Injury
Rapidly repairs mucosal damage caused by environmental stress, pathogens, or mycotoxins. Restores tight junction integrity to prevent nutrient leakage and secondary infection. Sustains absorptive capacity through the demanding post-peak laying period, directly protecting egg quality metrics. Strengthen Mucosal Immune Defense
Enhances mucosal immune barrier function, promotes IgA secretion, and reduces pathogenic infection risk. Supports immune resilience through the long laying cycle and during vaccination stress periods. Improve Feed Utilization and Nutrient Absorption
Promotes digestive enzyme secretion and nutrient transporter expression. Improves calcium, phosphorus, and protein absorption efficiency — the direct inputs for eggshell quality, egg weight, and sustained laying rate. gEGF is not an antibiotic and does not induce resistance. Its mechanism — receptor-mediated cellular signaling — is fully compatible with antibiotic-free (ABF) production programs. |
What are the Benefits of Tipek（Laying Hens)? |
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For Young Hens / Pullets (growing stage): |
For Laying Hens: |
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| ROI Note: A farm with 76,000 laying hens at 90% laying rate produces ~68,400 eggs/day. A 35.7% reduction in breakage rate (1.68% → 1.08%) saves ~410 eggs per day. The cost of Tipek supplementation is typically recovered within days of use. |
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| Trial Data — Verified in Commercial Settings |
| Trial 1 Pullet Trial A total of 18,400 Hailan Gray layer pullets at 21 days of age were selected anddivided into a control group and a treatment group, with 9,200 birds per group. The experimental period lasted 35 days. The control group was fed a basal diet, while the treatment group received the basal diet supplemented with TIPEK at 100 g/t. |
Group | Body weight at 56 d (g) | Shank length at 56 d (mm) | Intestinal length at 56 d (cm) |
| Control group (basal diet) |
1563 | 52.38 | 183.6 | |
| Trial group (added with 100 g/t TIPEK) | 1596 | 52.54 | 194.6 | |
| Improvement | +33 | +0.16mm | +11cm |
| Trial 2 White Feather Broiler Trial A total of 76,344 Jingfen No. 2 layer pullets were selected and divided into a control group and a treatment group. The experimental period lasted 35 days. The control group was fed a basal diet, while the treatment group received the basal diet supplemented with TIPEK at 100 g/t. |
Group | House population at 480 d (n) | House population at 515 d (n) | Survival rate (%) | Laying rate (%) | Egg weight (g) | FCR (feed:egg) | Cracked egg rate (%) |
| Control group (basal diet) | 73514 | 61133 | 80.20 | 90.10 | 61.3 | 2.10 | 1.68 | |
| Trial group (added with 100 g/t TIPEK) |
73933 | 61948 | 80.34 | 91.20 | 61.9 | 2.05 | 1.08 | |
| Improvement | +0.14% | +1.1% | +0.6 | -0.05 | -35.7% |
| Performance Improvements | ||
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Fast-Growing Broilers |
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Weight Gain +3% to 5% improvement |
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Tibia length +2% to 3% improvement |
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Intestinal length +5% to 8% improvement |
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| For Local / Heritage Breeds: |
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Laying rate +1% to 2% improvement |
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Egg weight (g) +1% to 2% improvement |
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FCR Reduction -2% to 4% decrease |
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Broken egg rate (%) -30% to 50% decrease |
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TIPEK FAQ |
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Q: What is the most compelling reason to use Tipek for laying hens? |
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Q: When should Tipek be introduced in the laying cycle? |
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| Q: Why use species-homologous gEGF rather than other EGF sources? A: Tipek (Laying Hens) uses recombinant Gallus EGF — the sequence identical to the bird's own EGF. This maximizes binding affinity to poultry EGFR and ensures full biological activity. It is produced via precision yeast fermentation with no animal-derived inputs, eliminating any biosafety concerns. |
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Q: Can Tipek be used throughout the full laying cycle? |
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Recommended Dosage |
Packaging |
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