Name: Tipek（Swine）
Brand: My Web Site
SKU: 00103
Availability: InStock
Rating: 5 (1 reviews)

Home > Epidermal Growth Factor

Description

Swine	Poultry	Ruminant	Aquaculture	Laying Hens
What is Tipek (Swine)?

Tipek (Swine) is a functional bioactive peptide product used as a swine feed additive. Its core active ingredient is recombinant porcine Epidermal Growth Factor (pEGF) — a naturally occurring growth factor that is the primary driver of intestinal development and mucosal repair in pigs.

EGF is the most abundant growth factor in sow milk, present at approximately 124 μg/L. At weaning, piglets abruptly lose this critical source of intestinal support — exactly when gut health pressure is highest. Tipek supplements exogenous EGF to fill this gap, maintaining intestinal structural integrity and absorptive function through the most vulnerable stage of swine production.

How Does Tipek (Swine) Work?

EGF binds to EGF receptors (EGFR) expressed on intestinal epithelial cells throughout the small intestine and colon. This activates a signaling cascade that drives four measurable outcomes:

Promote Intestinal Development

Stimulates intestinal epithelial cell metabolism, growth, proliferation, and differentiation. Increases villus height and crypt depth, promotes intestinal tissue maturation. Supports longer, healthier intestines with greater absorptive surface area.

Repair Mucosal Injury

Rapidly repairs epithelial damage caused by pathogens, mycotoxins, feed stress, or weaning transition. Strengthens tight junction proteins to restore barrier integrity and reduce leaky gut. Reduces pathogen colonization by competing for epithelial binding sites.

Strengthen Intestinal Immune Defense

Enhances mucosal immune function and the structural barrier role of the intestinal mucosa. Reduces the risk of pathogenic infection and improves disease resistance.

Improve Feed Utilization

Stimulates digestive enzyme secretion (trypsin, alkaline phosphatase, sucrase, maltase, lactase). Promotes nutrient transport carrier expression. Improves the digestion and absorption efficiency of feed nutrients — converting more of every kilogram of feed into growth.

What are the Benefits of Tipek?

For Nursery Piglets:	For Growing and Finishing Pigs:	For Sows:

Compensates for the loss of milk-borne EGF at weaning Promotes intestinal development and reduces post-weaning diarrhea Improves feed digestibility and nutrient absorption Reduces mortality during the nursery phase	Maintains gut integrity under stress (feed changes, transport, regrouping) Improves feed conversion efficiency Reduces subclinical gut injury that silently reduces performance	Strengthens immune function during gestation and lactation Improves colostrum quality and passive immunity transfer to piglets Supports reproductive performance and litter vitality

Trial Data — Verified in Commercial Settings

Trial 1 A total of 2,000 piglets at 30 days of age were selected and divided into a control group and a test group, with 1,000 piglets per group. The trial period lasted 50 days. The control group was fed a basal diet, while the test group was fed the basal diet supplemented with 200 g/T of TIPEK	Parameter	Control Group	Tipek Group	Improvement
	Initial number (heads)	1000	1000
	Final number (heads)	980	980	+0.8
	Survival rate (%)	98.0	98.8	+0.8
	Initial AVG BW (kg)	8.23	8.22
	Final AVG BW(kg)	33.31	35.62	+2.32
	ADFI (kg)	43.89	44.66	+0.77
	FCR	1.75	1.63	-0.12

Trial 2-Finishing Pig Trial A total of 240 finishing pigs with an initial body weight of approximately 97 kg were selected and divided into a control group and a test group, with 120 pigs per group. The trial period lasted 28 days. The control group was fed a basal diet, while the test group was fed the basal diet supplemented with 100 g/T of TIPEK	Parameter	Control Group	Tipek Group	Improvement
	Number of pigs (heads)	120	120
	Initial BW (kg)	97.45	97.28
	Final BW (kg)	121.18	122.37	+1.36
	Feeding days (days)	28	28
	Total feed intake (kg)	83.72	84.28
	ADFI (kg)	2.99	3.01
	Total weight gain (kg)	23.73	25.09
	Average daily gain (g)	845.7	896.1	+48.6
	FCR	3.53	3.36	−0.17

Improvement of Intestinal Microflora Environment The intestinal microflora environment of animals is improved, with beneficial bacteria significantly increased and gut health status enhanced.	Microbial Species	Control Group	Test Group	Improvement (Fold)
	Bacteroides spp.	3690	2180	0.6
	Butyrate-producing bacteria	13	37	2.8
	Clostridium spp.	692	1584	2.3
	Lactobacillus spp.	712	957	1.34
	Ruminococcus spp.	7270	10132	1.4

Performance Improvements
		Weight Gain +5% to +8% improvement
		Feed Intake +4% to 6% improvement
		FCR Reduction -3% to 5% decrease
		Diarrhea Reduction -30% to 50% decrease
		Digestibility +3% to 5% Improvement
		Intestinal development: +8% to 10% increase in length; 2–3× increase in beneficial gut bacteria
		Coat appearance visibly smoother and glossier within 7–10 days
	TIPEK® SWINE	Commercial trials demonstrate significant performance improvements

TIPEK FAQ

Q:Why Is Tipek Different from Other EGF Products? A: Tipek uses recombinant porcine EGF (pEGF) produced via yeast fermentation (Pichia pastoris expression system). The active sequence is identical to naturally occurring pig EGF — maximizing receptor binding affinity and biological activity in swine. Bioactivity testing shows Tipek's pEGF delivers 3.97× the proliferative effect of standard human recombinant EGF at equivalent concentration. Unlike formaldehyde-treated or heat-inactivated alternatives on the market, Tipek uses a precision spray-drying process that preserves full peptide activity through the manufacturing and storage cycle.

Q: Is Tipek effective even without active disease challenge? A: Yes. Even in healthy herds, sub-optimal intestinal development after weaning is universal. Tipek improves baseline intestinal absorptive capacity and barrier function, which translates into measurable FCR and growth improvements regardless of disease status. The effect is amplified during disease challenge periods.

Q: How quickly can results be observed? A: Skin and coat condition improvement is typically visible within 7–10 days. Diarrhea rate reduction is usually apparent within the first 14 days. FCR and weight gain improvements are measurable over a full growth phase (4–6 weeks).

Q: Can Tipek be used alongside antibiotics or other feed additives? A: Yes. Tipek is fully compatible with antibiotics, vitamins, minerals, enzymes, probiotics, and mycotoxin binders. No known antagonistic interactions. It can be used as a standalone gut health additive or as part of a comprehensive health program.

Q: Is Tipek safe for all swine stages including pregnant sows? A: Yes. EGF is naturally produced in swine tissue and is metabolized as a normal dietary protein. No withdrawal period is required and there are no drug residue concerns.

Q: Why is recombinant porcine EGF better than using natural sow colostrum? A: Natural colostrum is highly variable in EGF content and cannot be standardized or used at scale. Recombinant pEGF from Tipek delivers a precise, consistent, biologically active dose that can be incorporated into any feed formulation and used across the entire production cycle.

Recommended Dosage

Packaging

Animal Stage		Dosage(g/ton feed)
	Nursery(Creep/Starter)	200
	Piglets	150
	Grower-Finisher Pigs	100
	Sows	200

NOTE：Dosage can be adjusted based on actual farm conditions and disease challenge level. Long-term continuous use is recommended for optimal results.

Packaging: 25 kg/bag \| Storage: Cool and dry place \| Shelf life: 24months